6-(1,4,5,6-Tetrahydro-4-methyl-6-oxo-3-pyridazinyl)-2H-1,4-benzoxazin-3(4H)-one → 6-(3,4-Dihydro-1,4(2H)-benzoxazin-6-yl)-2,3,4,5-tetrahydro-5-methylpyridazin-3-one

HRID 2414195Notes

Reaction equation

HRID 2414195 reaction equation
C([N:4]1[C:9]2[CH:10]=[C:11]([C:14]3[CH:15]([CH3:21])[CH2:16][C:17](=[O:20])[NH:18][N:19]=3)[CH:12]=[CH:13][C:8]=2[O:7][CH2:6][CH2:5]1)(=O)C.CS(N1C2C=C(C3C(C)CC(=O)NN=3)C=CC=2OCC1)(=O)=O.CC1CNC2C=C(C3CCC(=O)NN=3)C=CC=2O1.CC1CNC2C=C(C3C(C)CC(=O)NN=3)C=CC=2O1.O=C1NC2C=C(C3CCC(=O)NN=3)C=CC=2OC1.O=C1NC2C=C(C3C(C)CC(=O)NN=3)C=CC=2OC1>>[O:7]1[C:8]2[CH:13]=[CH:12][C:11]([C:14]3[CH:15]([CH3:21])[CH2:16][C:17](=[O:20])[NH:18][N:19]=3)=[CH:10][C:9]=2[NH:4][CH2:5][CH2:6]1

Participants

7

Reactant 6

HCID 98166166-(1,4,5,6-Tetrahydro-4-methyl-6-oxo-3-pyridazinyl)-2H-1,4-benzoxazin-3(4H)-oneHCID 15599411HCID 15599411, compoundHCID 155994126-(3,4-dihydro-4-methanesulfonyl-1,4(2H)-benzoxazin-6-yl)-2,3,4,5-tetrahydro-5-methylpyridazin-3-oneHCID 155994136-(3,4-dihydro-2-methyl-1,4(2H)-benzoxazin-6-yl)-2,3,4,5-tetrahydropyridazin-3-oneHCID 15599414HCID 15599414, compoundHCID 15599415HCID 15599415, compound

Product 1

HCID 155994106-(3,4-Dihydro-1,4(2H)-benzoxazin-6-yl)-2,3,4,5-tetrahydro-5-methylpyridazin-3-one

Procedure

6-(4-acetyl-3,4-dihydro-1,4(2H)-benzoxazin-6-yl)-2,3,4,5-tetrahydro-5-methylpyridazin-3-one; 6-(3,4-dihydro-4-methanesulfonyl-1,4(2H)-benzoxazin-6-yl)-2,3,4,5-tetrahydro-5-methylpyridazin-3-one; 6-(3,4-dihydro-2-methyl-1,4(2H)-benzoxazin-6-yl)-2,3,4,5-tetrahydropyridazin-3-one; 6-(3,4-dihydro-2-methyl-1,4(2H)-benzoxazin-6-yl)-2,3,4,5-tetrahydro-5-methylpyridazin-3-one; 6-(3,4-dihydro-3-oxo-1,4(2H)-benzoxazin-6-yl)-2,3,4,5-tetrahydropyridazin-3-one; 6-(3,4-dihydro-3-oxo-1,4(2H)-benzoxazin-6-yl)-2,3,4,5-tetrahydro-5-methylpyridazin-3-one;

Sources & evidence

ORD record
ord-a2786dafb4cf4045afcd0caa508c9f2a
Source dataset
uspto-grants-1988_01
Patent number
US04721784

Reaction notes

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