HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Azide → (2-Azido-ethoxy)methyl-phosphonic acid-diethylester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Azide | HCID 33557 | — |
| Reactant | Diethyl ((2-chloroethoxy)methyl)phosphonate | HCID 10014096 | — |
| Catalyst | Tetrabutylammonium Bromide | HCID 74236 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | (2-Azido-ethoxy)methyl-phosphonic acid-diethylester | HCID 10037145 | — |
Reaction Steps
0,02 mol (2-chloroethoxy)methyl-phosphonic acid diethylester, 3 mmol tetrabutylammoniumbromide and 2,5 g sodiumazide are boiled in 50 ml toluol under reflux for 4 h. After cooling-off it is washed for three times with 25 ml water respectively. The watery phase may be extracted with toluol. The combined toluol phases are dried over sodiumsulfate and the solvent is removed in the vacuum. A yellow oil remains.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06812224B2 |
| Source dataset | uspto-grants-2004_11 |
| ORD ID | ord-1cc503066660426d933cb30d1cdcce9e |
| Source note | uspto-grants-2004_11 |