HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl formate → Formamide, N-[2-[3-(methylthio)phenyl]ethyl]-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl formate | HCID 8025 | — |
| Reactant | 3-(Methylthio)benzeneethanamine | HCID 10964901 | — |
| Reactant | N-[2-(3-Methoxyphenyl)ethyl]formamide | HCID 13562936 | — |
| Product | Formamide, N-[2-[3-(methylthio)phenyl]ethyl]- | HCID 10976389 | 78% |
Reaction Steps
A procedure identical to that described for the preparation of N-[2-(3-methoxy-phenyl)-ethyl]-formamide in Example 1 was followed using 2-(3-methylsulfanyl-phenyl)-ethylamine (7.4 g, 44 mmol) and formic acid ethyl ester (3.6 g, 48 mmol) to give the desired product (6.7 g, 78%). MS: 168.9 (M+1+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06812228B2 |
| Source dataset | uspto-grants-2004_11 |
| ORD ID | ord-c3c052edc8b5497db653696d7f076550 |
| Source note | uspto-grants-2004_11 |