Isopropylamine → 4-Chloro-N-isopropyl-3-nitrobenzenesulfonamide

HRID 2414316Notes

Reaction equation

HRID 2414316 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([S:8](Cl)(=[O:10])=[O:9])=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13].[CH:15]([NH2:18])([CH3:17])[CH3:16]>ClCCl>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([NH:18][CH:15]([CH3:17])[CH3:16])(=[O:10])=[O:9])=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13]

Participants

4

Reactant 2

HCID 6363IsopropylamineHCID 7323Benzenesulfonyl chloride, 4-chloro-3-nitro-

Product 1

HCID 667804-Chloro-N-isopropyl-3-nitrobenzenesulfonamide

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

4-Chloro-3-nitrobenzenesulfonyl chloride (2 g) and isopropylamine (2.1 ml) in dichloromethane (30 ml) was stirred at room temperature for 2 h. The mixture was washed with water, 2M hydrochloric acid, water, dried and evaporated under reduced pressure. Yield 2.2 g.

Workup

  1. washThe mixture was washed with water, 2M hydrochloric acid, water
  2. customdried
  3. customevaporated under reduced pressure

Sources & evidence

ORD record
ord-b4abb9eaa9a34722afce9318ab1c1fc8
Source dataset
uspto-grants-2004_11
Patent number
US06812226B2

Reaction notes

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