1-(4-Piperidinyl)-1,2-dihydro-4H-3,1-benzoxazin-2-one hydrochloride → HCID 22644582, compound

HRID 2414323Notes

Reaction equation

HRID 2414323 reaction equation
Cl[C:2]1[CH:13]=[CH:12][C:5]([C:6]([NH:8][CH:9]([CH3:11])[CH3:10])=[O:7])=[CH:4][C:3]=1[C:14]#[N:15].Cl.[NH:17]1[CH2:22][CH2:21][CH:20]([N:23]2[C:28]3[CH:29]=[CH:30][CH:31]=[CH:32][C:27]=3[CH2:26][O:25][C:24]2=[O:33])[CH2:19][CH2:18]1>>[C:14]([C:3]1[CH:4]=[C:5]([CH:12]=[CH:13][C:2]=1[N:17]1[CH2:18][CH2:19][CH:20]([N:23]2[C:28]3[CH:29]=[CH:30][CH:31]=[CH:32][C:27]=3[CH2:26][O:25][C:24]2=[O:33])[CH2:21][CH2:22]1)[C:6]([NH:8][CH:9]([CH3:11])[CH3:10])=[O:7])#[N:15]

Participants

3

Reactant 2

HCID 220630891-(4-Piperidinyl)-1,2-dihydro-4H-3,1-benzoxazin-2-one hydrochlorideHCID 22644644HCID 22644644, compound

Product 1

HCID 22644582HCID 22644582, compound

Procedure

The title compound was prepared from the product of step (iii) (0.29 g) and 1-piperidin-4-yl-1,4-dihydro-2H-3,1-benzoxazin-2-one hydrochloride (0.3 g) using the method of example 115 step (ii). Yield 0.073 g.

Sources & evidence

ORD record
ord-f337a9096c094dc7ae89fcaefcb61815
Source dataset
uspto-grants-2004_11
Patent number
US06812226B2

Reaction notes

Loading…