反应详情

Isopropylsulphonyl chloride (0.03 ml) was added to a stirred solution of the product from example 120 step (ii) (0.05 g), pyridine (0.1 ml) in acetonitrile (0.9 ml) at room temperature. The mixture was stirred overnight, partitioned between ethyl acetate and water, the organics separated, washed with water, dried, and evaporated under reduced pressure. Purification was by chromatography eluting with 40% ethyl acetate/isohexane. Yield 0.015 g.

1. custompartitioned between ethyl acetate and water
2. washthe organics separated, washed with water
3. customdried
4. customevaporated under reduced pressure
5. customPurification
6. washeluting with 40% ethyl acetate/isohexane