HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Aminopropanol → HCID 22644579, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Aminopropanol | HCID 5126 | — |
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | 5-Chloro-6-[4-(2-oxo-2h-3,1-benzoxazin-1(4h)-yl)piperidin-1-yl]pyridine-3-carboxylic acid | HCID 22644584 | — |
| Product | HCID 22644579 | HCID 22644579 | — |
Reaction Steps
The title compound was prepared from the product of example 148 step (i) (0.14 g), carbonyldiimidazole (0.064 g) and DL-2-amino-1-propanol (0.05 g) using the method of example 115 step (i). Purification was by chromatography eluting with 20% ethyl acetate/isohexane. Yield 0.04 g as a solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06812226B2 |
| Source dataset | uspto-grants-2004_11 |
| ORD ID | ord-2df0c5c36ed0420291f47e83014acda5 |
| Source note | uspto-grants-2004_11 |