HCID 10910039, compound → HCID 60122358, compound

HRID 2414385Notes

Reaction equation

HRID 2414385 reaction equation
CC1OC(CCC(Cl)=O)=CC=1.[C:12]([O:16][C:17]([NH:19][CH:20]([CH2:24][C:25]1[O:26][C:27]([CH3:30])=[CH:28][CH:29]=1)[C:21]([OH:23])=[O:22])=[O:18])([CH3:15])([CH3:14])[CH3:13]>>[C:12]([O:16][C:17]([NH:19][C@@H:20]([CH2:24][C:25]1[O:26][C:27]([CH3:30])=[CH:28][CH:29]=1)[C:21]([OH:23])=[O:22])=[O:18])([CH3:15])([CH3:14])[CH3:13]

Participants

3

Reactant 2

HCID 10910039HCID 10910039, compoundHCID 22645440HCID 22645440, compound

Product 1

HCID 60122358HCID 60122358, compound

Procedure

3-(5-Methyl-furan-2-yl)-propionyl chloride (H. Kotsuki et al., Bull. Chem. Soc. Jpn., 1984, 57, 3339) is converted to (S) 2-(tert-butoxycarbonylamino)-3-(5-methyl-furan-2-yl)-propionic acid according to the Evans amino acid protocol (J. Am. Chem. Soc. 1990, 112, 4011).

Sources & evidence

ORD record
ord-955344f4595e4b3193bb995bad42c890
Source dataset
uspto-grants-2004_11
Patent number
US06812237B2

Reaction notes

Loading…