Sodium Hydroxide → 4-(3,4-Dimethoxybenzoyl)benzoic acid

HRID 2414434Notes

Reaction equation

HRID 2414434 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:18]=[CH:19][C:20]=1[O:21][CH3:22])[C:6]([C:8]1[CH:17]=[CH:16][C:11]([C:12]([O:14]C)=[O:13])=[CH:10][CH:9]=1)=[O:7].[OH-].[Na+]>C(O)C>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:18]=[CH:19][C:20]=1[O:21][CH3:22])[C:6]([C:8]1[CH:17]=[CH:16][C:11]([C:12]([OH:14])=[O:13])=[CH:10][CH:9]=1)=[O:7]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 22645197Methyl 4-(3,4-dimethoxybenzoyl)benzoate

Product 1

HCID 226452014-(3,4-Dimethoxybenzoyl)benzoic acid

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

1.3 g (4.33 mmol) of methyl 4-(3,4-dimethoxybenzoyl)benzoate was dissolved in 50 ml of ethanol. 7 ml of 1 N sodium hydroxide solution was added to the obtained solution, and they were stirred overnight. The solvent was evaporated, and the residue was washed with ethyl acetate and then filtered to obtain the title compound.

Workup

  1. customThe solvent was evaporated
  2. washthe residue was washed with ethyl acetate
  3. filtrationfiltered

Sources & evidence

ORD record
ord-53d65ee6a16f42aca430a61635896b25
Source dataset
uspto-grants-2004_11
Patent number
US06812231B2

Reaction notes

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