HCID 11414048, compound → HCID 12040467, compound

Participants

Reaction Steps

500 mg (2 mmol) of 9-methylenecyclohexadecanone are introduced into 25 ml of ethyl acetate, and 25 mg of Pd/C are added thereto. Hydrogenation is then carried out at 40° C. and standard hydrogen pressure for 5 h. When the reaction is complete, the mixture is filtered over Celite, and the crude product is freed from solvent. Purification by flash chromatography (cyclohexane/EtOAc=25:1) gives 475 mg (94%) of a colorless oil.

Provenance & Evidence