HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,5-Dichloropyridine → 3-(5-Chloro-3-pyridyl)-3,7-diazabicyclo[3.3.0]octane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,5-Dichloropyridine | HCID 17153 | — |
| Reactant | Octahydropyrrolo(3,4-c)pyrrole | HCID 21867666 | — |
| Product | 3-(5-Chloro-3-pyridyl)-3,7-diazabicyclo[3.3.0]octane | HCID 9877882 | — |
Reaction Steps
3,5-Dichloropyridine (1 eq.), 3.7-Diazabicyclo[3.3.0]octane (1 eq.) and palladacycle (0.2%) [Herrmann W A, Brossmer C, Öfele K, Reisinger, C-P, Priermeier, T, Beller M, and Fischer, H; Angew. Chem. Int. Ed. Enql. 1995 34 1844] is stirred at 160° C. for 24 hours. Workup-procedure A/B.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06815438B2 |
| Source dataset | uspto-grants-2004_11 |
| ORD ID | ord-fe41733071f4403c96ecd8ee5059648f |
| Source note | uspto-grants-2004_11 |