1-Methyl-4-piperidone → HCID 781991, compound

HRID 2414892Notes

Reaction equation

HRID 2414892 reaction equation
[CH3:1][N:2]1[CH2:7][CH2:6][C:5](=O)[CH2:4][CH2:3]1.[F:9][C:10]([F:20])([F:19])[C:11]1[CH:18]=[CH:17][C:14]([CH2:15][NH2:16])=[CH:13][CH:12]=1>>[F:9][C:10]([F:19])([F:20])[C:11]1[CH:18]=[CH:17][C:14]([CH2:15][NH:16][CH:5]2[CH2:6][CH2:7][N:2]([CH3:1])[CH2:3][CH2:4]2)=[CH:13][CH:12]=1

Participants

3

Reactant 2

HCID 740491-Methyl-4-piperidoneHCID 768044-(Trifluoromethyl)benzylamine

Product 1

HCID 781991HCID 781991, compound

Procedure

Starting materials: 1-Methyl-4-piperidone (1.13 g, 10.0 mmol, 1.0 eq.), 4-trifluoromethylbenzylamine (1.75 g, 1.0 eq.).

Sources & evidence

ORD record
ord-7f94c7550df4476396c23ed2d374220f
Source dataset
uspto-grants-2004_11
Patent number
US06815458B2

Reaction notes

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