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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2414944Generated: October 30, 2026

Propanal → (5R)-5,12-diethyl-9-fluoro-5-hydroxy-4,5,13,15-tetrahydro-1H,3H-oxepino[3',4':6,7]indolizino[1,2-b]quinoline-3,15-dione

https://huagongshe.com/reaction/2414944

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPropanalHCID 527—
Reactant(5R)-5-ethyl-9-fluoro-5-hydroxy-4,5,13,15-tetrahydro-1H,3H-oxepino[3',4':6,7]indolizino[1,2-b]quinoline-3,15-dioneHCID 9929755—
Product(5R)-5,12-diethyl-9-fluoro-5-hydroxy-4,5,13,15-tetrahydro-1H,3H-oxepino[3',4':6,7]indolizino[1,2-b]quinoline-3,15-dioneHCID 69478365—

Reaction Steps

The product of Example 84 is treated with propionaldehyde according to a procedure similar to Stage 95e in order to produce the expected solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06815546B2
Source datasetuspto-grants-2004_11
ORD IDord-3cedbb6813be4a15b3c0a66488815ac8
Source noteuspto-grants-2004_11