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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2414948Generated: October 26, 2026

Hexanal → (5R)-5-ethyl-9-fluoro-5-hydroxy-12-pentyl-4,5,13,15-tetrahydro-1H,3H-oxepino[3',4':6,7]indolizino[1,2-b]quinoline-3,15-dione

https://huagongshe.com/reaction/2414948

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHexanalHCID 6184—
Reactant(5R)-5-ethyl-9-fluoro-5-hydroxy-4,5,13,15-tetrahydro-1H,3H-oxepino[3',4':6,7]indolizino[1,2-b]quinoline-3,15-dioneHCID 9929755—
Product(5R)-5-ethyl-9-fluoro-5-hydroxy-12-pentyl-4,5,13,15-tetrahydro-1H,3H-oxepino[3',4':6,7]indolizino[1,2-b]quinoline-3,15-dioneHCID 69591007—

Reaction Steps

The product of Example 84 is treated with hexanal according to a procedure similar to Stage 95e in order to produce the expected solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06815546B2
Source datasetuspto-grants-2004_11
ORD IDord-01c68c4c459247559fd50c78298eb9a9
Source noteuspto-grants-2004_11