Phenoxyacetic Acid → Phenoxyacetyl chloride

HRID 2414988Notes

Reaction equation

HRID 2414988 reaction equation
[O:1]([CH2:8][C:9]([OH:11])=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.S(Cl)([Cl:14])=O>>[O:1]([CH2:8][C:9]([Cl:14])=[O:11])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 19188Phenoxyacetic AcidHCID 24386Thionyl Chloride

Product 1

HCID 69703Phenoxyacetyl chloride

Procedure

Phenoxyacetic acid (d5) was treated with 25 ml of thionyl chloride and stirred for 18 hours at room temperature. After the end of the reaction, the reaction mixture was concentrated under vacuum at 30° C. to provide phenoxyacetyl chloride (4.8 g).

Workup

  1. customAfter the end of the reaction
  2. concentrationthe reaction mixture was concentrated under vacuum at 30° C.

Sources & evidence

ORD record
ord-acbf6eedf11b4a9c84361ade812d1981
Source dataset
uspto-grants-2004_11
Patent number
US06818200B2

Reaction notes

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