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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2415013Generated: October 25, 2026

HCID 178418361, compound → HCID 178453600, compound

https://huagongshe.com/reaction/2415013

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 178418361HCID 178418361—
ReactantHCID 178453603HCID 178453603—
CatalystPlatinum oxide (PtO)HCID 82844—
SolventEthyl AcetateHCID 8857—
ProductHCID 178453600HCID 178453600—

Reaction Steps

trans-(4-Azidomethyl-cyclohexylmethyl)-carbamic acid tert-butyl ester (24 g) in ethyl acetate (1 liter) is hydrogenated over platinumoxide (2.4 g) at ambient temperature under atmospheric pressure of hydrogen. The catalyst is filtered-off and the filtrate concentrated to yield trans-(4-aminomethyl-cyclohexylmethyl)-carbamic acid tert-butyl ester as an oil. Rf(C2) 0.41.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06818445B2
Source datasetuspto-grants-2004_11
ORD IDord-4d16b1af04f2437e99073bdd9c3f35eb
Source noteuspto-grants-2004_11