HRID2415164

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID2736946

1-(6-methylpyridin-2-yl)piperazine

C10H15N3

结构：O=C(NCc1ccc(F)cc1)C1(CCCCBr)c2ccccc2-c2ccccc21

HCID22636238

未命名化合物

PRODUCTS

生成物

结构：Cc1cccc(N2CCN(CCCCC3(C(=O)NCc4ccc(F)cc4)c4ccccc4-c4ccccc43)CC2)n1

HCID22640164

未命名化合物

PROCEDURE

实验过程

Prepared analogously to Example 2 b from 1-(6-methyl-pyridin-2-yl)-piperazine and 9-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid-4-fluorobenzyl-amide.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-c3e0b92cb9ca4ce1a2e946bf5c43824c
来源数据集: uspto-grants-2004_11
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06818644B1
来源说明: uspto-grants-2004_11

反应 SMILES

[CH3:1][C:2]1[N:7]=[C:6]([N:8]2[CH2:13][CH2:12][NH:11][CH2:10][CH2:9]2)[CH:5]=[CH:4][CH:3]=1.[F:14][C:15]1[CH:42]=[CH:41][C:18]([CH2:19][NH:20][C:21]([C:23]2([CH2:36][CH2:37][CH2:38][CH2:39]Br)[C:35]3[CH:34]=[CH:33][CH:32]=[CH:31][C:30]=3[C:29]3[C:24]2=[CH:25][CH:26]=[CH:27][CH:28]=3)=[O:22])=[CH:17][CH:16]=1>>[F:14][C:15]1[CH:16]=[CH:17][C:18]([CH2:19][NH:20][C:21]([C:23]2([CH2:36][CH2:37][CH2:38][CH2:39][N:11]3[CH2:12][CH2:13][N:8]([C:6]4[CH:5]=[CH:4][CH:3]=[C:2]([CH3:1])[N:7]=4)[CH2:9][CH2:10]3)[C:35]3[CH:34]=[CH:33][CH:32]=[CH:31][C:30]=3[C:29]3[C:24]2=[CH:25][CH:26]=[CH:27][CH:28]=3)=[O:22])=[CH:41][CH:42]=1