Diethyl[2-(4-nitrophenoxy)ethyl]amine → 4-(2-(Diethylamino)ethoxy)aniline

Participants

Reaction Steps

A solution of diethyl-[2-(4-nitro-phenoxy)-ethyl]-amine (6.8 g, 28.3 mmol) (from Step A above) and 200 mg of 10% palladium-on-carbon in ethanol (150 mL) was hydrogenated at 20 psi in a Parr shaker for 1 hour. The mixture was filtered through Celite™ and the solvent was evaporated to give 5.36 g, (90%) 4-(2-diethylamino-ethoxy)-phenylamine.

Provenance & Evidence