Cyanamide → HCID 22641032, compound

HRID 2415287Notes

Reaction equation

HRID 2415287 reaction equation
[N:1]#[C:2][NH2:3].C(OC(=O)[N:10]([CH:23]([CH3:25])[CH3:24])[CH2:11][CH2:12][O:13][C:14]1[CH:19]=[CH:18][C:17]([N:20]=[C:21]=[S:22])=[CH:16][CH:15]=1)(C)(C)C.Br[CH2:28][C:29]([C:31]1[CH:40]=[CH:39][C:34]2[O:35][CH2:36][CH2:37][O:38][C:33]=2[CH:32]=1)=[O:30]>>[NH2:1][C:2]1[N:3]=[C:21]([NH:20][C:17]2[CH:16]=[CH:15][C:14]([O:13][CH2:12][CH2:11][NH:10][CH:23]([CH3:24])[CH3:25])=[CH:19][CH:18]=2)[S:22][C:28]=1[C:29]([C:31]1[CH:40]=[CH:39][C:34]2[O:35][CH2:36][CH2:37][O:38][C:33]=2[CH:32]=1)=[O:30]

Participants

4

Reactant 3

HCID 9864CyanamideHCID 27761712-Bromo-1-(2,3-dihydro-1,4-benzodioxin-6-yl)ethan-1-oneHCID 86590645HCID 86590645, compound

Product 1

HCID 22641032HCID 22641032, compound

Procedure

This compound was prepared from cyanamide, isopropyl-[2-(4-isothiocyanato-phenoxy)-ethyl]-carbamic acid tert-butyl ester of Example 135 and 2-bromo-1-(2,3-dihydro-benzo[1,4]dioxin-6-yl)ethanone (Maybridge Chemical) following a procedure similar to Example 130. Mass spectrum (ES) MH+=455.

Sources & evidence

ORD record
ord-b5cedea106864af49fb5fefebfde80aa
Source dataset
uspto-grants-2004_11
Patent number
US06818663B2

Reaction notes

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