Cyanamide → HCID 22641046, compound

HRID 2415288Notes

Reaction equation

HRID 2415288 reaction equation
[N:1]#[C:2][NH2:3].C(OC(=O)[N:10]([CH:23]([CH3:25])[CH3:24])[CH2:11][CH2:12][O:13][C:14]1[CH:19]=[CH:18][C:17]([N:20]=[C:21]=[S:22])=[CH:16][CH:15]=1)(C)(C)C.[O:27]1[C:31]2[CH:32]=[CH:33][C:34]([C:36](=[O:39])[CH2:37]Br)=[CH:35][C:30]=2[O:29][CH2:28]1>>[NH2:1][C:2]1[N:3]=[C:21]([NH:20][C:17]2[CH:16]=[CH:15][C:14]([O:13][CH2:12][CH2:11][NH:10][CH:23]([CH3:24])[CH3:25])=[CH:19][CH:18]=2)[S:22][C:37]=1[C:36]([C:34]1[CH:33]=[CH:32][C:31]2[O:27][CH2:28][O:29][C:30]=2[CH:35]=1)=[O:39]

Participants

4

Reactant 3

HCID 9864CyanamideHCID 2437771-(1,3-Dioxaindan-5-yl)-2-bromoethan-1-oneHCID 86590645HCID 86590645, compound

Product 1

HCID 22641046HCID 22641046, compound

Procedure

This compound was prepared from cyanamide, isopropyl-[2-(4-isothiocyanato-phenoxy)-ethyl]-carbamic acid tert-butyl ester of Example 135 and 1-benzo[1,3]dioxol-5-yl-2-bromo-ethanone (of Example 132) following a procedure similar to Example 130. Mass spectrum (ES) MH+=441.

Sources & evidence

ORD record
ord-18f75923baab40c9beca3287c69422f5
Source dataset
uspto-grants-2004_11
Patent number
US06818663B2

Reaction notes

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