Cyanamide → HCID 10434604, compound

HRID 2415290Notes

Reaction equation

HRID 2415290 reaction equation
[N:1]#[C:2][NH2:3].[N:4]([C:7]1[CH:20]=[CH:19][C:10]([O:11][CH2:12][CH2:13][N:14]2[CH2:18][CH2:17][CH2:16][CH2:15]2)=[CH:9][CH:8]=1)=[C:5]=[S:6].Br[CH2:22][C:23]([C:25]1[CH:26]=[CH:27][C:28]2[O:32][CH2:31][CH:30]([CH3:33])[C:29]=2[CH:34]=1)=[O:24]>>[NH2:1][C:2]1[N:3]=[C:5]([NH:4][C:7]2[CH:8]=[CH:9][C:10]([O:11][CH2:12][CH2:13][N:14]3[CH2:15][CH2:16][CH2:17][CH2:18]3)=[CH:19][CH:20]=2)[S:6][C:22]=1[C:23]([C:25]1[CH:26]=[CH:27][C:28]2[O:32][CH2:31][CH:30]([CH3:33])[C:29]=2[CH:34]=1)=[O:24]

Participants

4

Reactant 3

HCID 9864CyanamideHCID 118461221-(2-(4-Isothiocyanatophenoxy)ethyl)pyrrolidineHCID 22640993HCID 22640993, compound

Product 1

HCID 10434604HCID 10434604, compound

Procedure

This compound was prepared from cyanamide, 1-[2-(4-Isothiocyanato-phenoxy)-ethyl]-pyrrolidine (from Example 5) and 2-bromo-1-(3-methyl-2,3-dihydro-benzofuran-5-yl)ethanone (from Example 138) following a procedure similar to Example 130. Mass spectrum (ES) MH+=465.

Sources & evidence

ORD record
ord-99b0597807034a21a5eb5841a4dac6e1
Source dataset
uspto-grants-2004_11
Patent number
US06818663B2

Reaction notes

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