N-[2-Hydroxy-3-(4-methoxyphenoxy)propyl]-1,1-dimethyl-2-(4-methoxyphenyl)ethylamine Hydrochloride → N-[2-hydroxy-3-(3-cyanophenoxy)propyl]-1,1-dimethyl-2-(4-methoxyphenyl)ethylamine Hydrochloride

HRID 2415351Notes

Reaction equation

HRID 2415351 reaction equation
[ClH:1].O[C@H](COC1C=CC(C(C)(C)C)=CC=1)[CH2:4][NH:5]C(C)(C)CC1C=CC(OC)=CC=1.Cl.[OH:31][CH:32]([CH2:47][O:48][C:49]1[CH:54]=[CH:53][C:52](OC)=[CH:51][CH:50]=1)[CH2:33][NH:34][C:35]([CH3:46])([CH3:45])[CH2:36][C:37]1[CH:42]=[CH:41][C:40]([O:43][CH3:44])=[CH:39][CH:38]=1>>[ClH:1].[OH:31][CH:32]([CH2:47][O:48][C:49]1[CH:50]=[CH:51][CH:52]=[C:53]([C:4]#[N:5])[CH:54]=1)[CH2:33][NH:34][C:35]([CH3:46])([CH3:45])[CH2:36][C:37]1[CH:38]=[CH:39][C:40]([O:43][CH3:44])=[CH:41][CH:42]=1

Participants

3

Reactant 2

HCID 22640899N-[2-Hydroxy-3-(4-methoxyphenoxy)propyl]-1,1-dimethyl-2-(4-methoxyphenyl)ethylamine HydrochlorideHCID 69471426(S)-N-[2-Hydroxy-3-(4-t-butylphenoxy)propyl]-1,1-dimethyl-2-(4-methoxyphenyl)ethylamine Hydrochloride

Product 1

HCID 22640852N-[2-hydroxy-3-(3-cyanophenoxy)propyl]-1,1-dimethyl-2-(4-methoxyphenyl)ethylamine Hydrochloride

Procedure

GC/EI-MS, m/z (rel. int.) 339 (M−15, 0.1), 234 (15), 233 (100), 121 (21), 102 (7), 90 (6).

Sources & evidence

ORD record
ord-4ff0b5bd8e744c57ab789498982f401b
Source dataset
uspto-grants-2004_11
Patent number
US06818660B2

Reaction notes

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