HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Bromoethyl ethyl ether → 2-(2-Ethoxy-ethyl)-6-(3-fluoro-benzyloxy)-1,2,3,4-tetrahydro-isoquinoline
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Bromoethyl ethyl ether | HCID 61141 | — |
| Edukt | 6-[(3-Fluorophenyl)methoxy]-1,2,3,4-tetrahydroisoquinoline | HCID 22641895 | — |
| Produkt | 2-(2-Ethoxy-ethyl)-6-(3-fluoro-benzyloxy)-1,2,3,4-tetrahydro-isoquinoline | HCID 22641951 | — |
Reaktionsschritte
As described for example 44, 6-(3-fluoro-benzyloxy)-1,2,3,4-tetrahydro-isoquinoline (0.100 g, 0.39 mmol) was converted to the tide compound (0.075 g, 59%) using 2-bromoethyl ethyl ether (0.072,g, 0.47 mmol) instead of 2-bromopropionamide. MS: m/e=330.4 (M+H+).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06818774B2 |
| Quelldatensatz | uspto-grants-2004_11 |
| ORD ID | ord-8de78d43a4444655959aaaf7ce60050e |
| Quellennotiz | uspto-grants-2004_11 |