Allyl bromide → HCID 22641323, compound

HRID 2415469Notes

Reaction equation

HRID 2415469 reaction equation
[CH3:1][C:2]1[CH:11]=[C:10]([N:12]2[CH2:16][CH2:15][CH2:14][CH2:13]2)[C:9]2[C:4](=[CH:5][C:6]([OH:17])=[CH:7][CH:8]=2)[N:3]=1.[CH2:18](Br)[CH:19]=[CH2:20]>>[CH2:20]([O:17][C:6]1[CH:5]=[C:4]2[C:9]([C:10]([N:12]3[CH2:16][CH2:15][CH2:14][CH2:13]3)=[CH:11][C:2]([CH3:1])=[N:3]2)=[CH:8][CH:7]=1)[CH:19]=[CH2:18]

Participants

3

Reactant 2

HCID 7841Allyl bromideHCID 1358041182-Methyl-4-pyrrolidin-1-yl-quinolin-7-ol

Product 1

HCID 22641323HCID 22641323, compound

Procedure

In analogy to example 6 there was prepared: on reaction of 2-methyl-4-pyrrolidin-1-yl-quinolin-7-ol with allyl bromide, whereby the product was isolated as free base, 7-allyloxy-2-methyl-4-pyrrolidin-1-yl-quinoline as a light yellow solid. EI mass spectrum, m/e: 268.2 (M calculated for C17H20N2O: 268).

Workup

  1. customIn analogy to example 6 there was prepared

Sources & evidence

ORD record
ord-dcb3f2b5151c4694a6e34f019627bca5
Source dataset
uspto-grants-2004_11
Patent number
US06818767B2

Reaction notes

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