HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Bromomethyl)benzonitrile → 4-(2-Methyl-4-pyrrolidin-1-yl-quinolin-7-yloxymethyl)-benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Bromomethyl)benzonitrile | HCID 86996 | — |
| Reactant | 2-Methyl-4-pyrrolidin-1-yl-quinolin-7-ol | HCID 135804118 | — |
| Product | 4-(2-Methyl-4-pyrrolidin-1-yl-quinolin-7-yloxymethyl)-benzonitrile | HCID 10291158 | — |
Reaction Steps
In analogy to example 6 there was prepared: on reaction of 2-methyl-4-pyrrolidin-1-yl-quinolin-7-ol with 4-bromomethyl benzonitrile whereby the product was isolated as free base, 4-(2-methyl-4-pyrrolidin-1-yl-quinolin-7-yloxymethyl)-benzonitrile as a brown solid. ISP mass spectrum, m/e: 344.4 (M+1 calculated for C22H21N3O: 344).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06818767B2 |
| Source dataset | uspto-grants-2004_11 |
| ORD ID | ord-6e25c70e5ffb484ca8abc93e41656e09 |
| Source note | uspto-grants-2004_11 |