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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2415488Generated: October 30, 2026

3-(Bromomethyl)-2-chloro-6-(trifluoromethyl)pyridine → HCID 22641451, compound

https://huagongshe.com/reaction/2415488

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Bromomethyl)-2-chloro-6-(trifluoromethyl)pyridineHCID 22641486—
Reactant2-Methyl-4-pyrrolidin-1-yl-quinolin-7-olHCID 135804118—
ProductHCID 22641451HCID 22641451—

Reaction Steps

In analogy to example 6 there was prepared: on reaction of 2-methyl-4-pyrrolidin-1-yl-quinolin-7-ol with 3-bromomethyl-2-chloro-6-trifluoromethyl-pyridine, whereby the product was isolated as free base, 7-(2-chloro-6-trifluoromethyl-pyridin-3-ylmethoxy)-2-methyl-4-pyrrolidin-1-yl-quinoline as a white solid. ISP mass spectrum, m/e: 422.2 (M+1 calculated for C21H19CIF3N3O: 422).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06818767B2
Source datasetuspto-grants-2004_11
ORD IDord-c85b4536ffe54b0baa0ce680c95152ee
Source noteuspto-grants-2004_11