HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl Ethyl Ketone → Ethanol heptane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl Ethyl Ketone | HCID 6569 | — |
| Reactant | Hydralazine Hydrochloride | HCID 9351 | — |
| Solvent | Methanol--water (1/1) | HCID 22242641 | — |
| Product | Ethanol heptane | HCID 22502148 | 78% |
Reaction Steps
A 10 parts 1-hydrazinophthalazine HCL (0.05 Molar) in 50% methanol-water are mixed with 1 part 2-butanone. After evaporation of solvents, 1-hydrazinophthalazine 2-butanone hydrazone is crystallized from ethanol-heptane (78% yield). [The Journal of Pharmacology and Experimental Therapeutics 205 (2): 418-425 (1978)].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06821974B2 |
| Source dataset | uspto-grants-2004_11 |
| ORD ID | ord-62577591c91a43728ef5b573b2903af6 |
| Source note | uspto-grants-2004_11 |