Stannous Chloride → HCID 57588233, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 8-nitro-3,4-dihydro-2H-benzo[b][1,4]dioxepine-6-carboxylic acid methyl ester (0.58 g), SnCl2 (2.17 g) and ethanol was refluxed at 70° C. for 2 hours. The reaction was poured over ice and the resulting aqueous solution treated with 5% NaHCO3 (pH 7-8) and extracted with EtOAc. The organic phase was dried with MgSO4 and solvent removed in vacuo to yield 0.318 g of product which was used directly in the next reaction. MS: M+ 224.

Provenance & Evidence