HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → 9-(4-bromo-butyl)-9H-fluorene-9-carboxylic Acid Chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 9-(4-bromobutyl)-9H-fluorene-9-carboxylic acid | HCID 10712518 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 9-(4-bromo-butyl)-9H-fluorene-9-carboxylic Acid Chloride | HCID 10522758 | — |
Reaction Steps
23 g (0.067 mol) of 9-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid are dissolved in 40 ml of dichloromethane, and combined with three drops of dimethylformamide and 6.96 ml (0.081 mol) of oxalyl chloride, dissolved in 10 ml of dichloromethane, under nitrogen at 0° C. The mixture is stirred for 3 hours at ambient temperature. Then the solvent is eliminated and the crude product is reacted further without additional purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06821967B2 |
| Source dataset | uspto-grants-2004_11 |
| ORD ID | ord-82bb8360e2e54040ba8a7f41f21b61b6 |
| Source note | uspto-grants-2004_11 |