Quipazine → 9-[4-(4-quinolin-2-yl-piperazin-1-yl)-butyl]-9H-fluorene-9-carboxylic acid-(benzyl)-amide

HRID 2415854Notes

Reaction equation

HRID 2415854 reaction equation
[CH2:1]([NH:8][C:9]([C:11]1([CH2:24][CH2:25][CH2:26][CH2:27]Br)[C:23]2[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=2[C:17]2[C:12]1=[CH:13][CH:14]=[CH:15][CH:16]=2)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[N:29]1([C:35]2[CH:44]=[CH:43][C:42]3[C:37](=[CH:38][CH:39]=[CH:40][CH:41]=3)[N:36]=2)[CH2:34][CH2:33][NH:32][CH2:31][CH2:30]1>>[CH2:1]([NH:8][C:9]([C:11]1([CH2:24][CH2:25][CH2:26][CH2:27][N:32]2[CH2:33][CH2:34][N:29]([C:35]3[CH:44]=[CH:43][C:42]4[C:37](=[CH:38][CH:39]=[CH:40][CH:41]=4)[N:36]=3)[CH2:30][CH2:31]2)[C:23]2[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=2[C:17]2[C:12]1=[CH:13][CH:14]=[CH:15][CH:16]=2)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 5011QuipazineHCID 22180445HCID 22180445, compound

Product 1

HCID 155523369-[4-(4-quinolin-2-yl-piperazin-1-yl)-butyl]-9H-fluorene-9-carboxylic acid-(benzyl)-amide

Procedure

Prepared analogously to Example 2b from 9-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid-(benzyl)-amide and 2-(piperazin-1-yl)-quinoline.

Sources & evidence

ORD record
ord-50560c683f744eb5a437d44ee2fe4149
Source dataset
uspto-grants-2004_11
Patent number
US06821967B2

Reaction notes

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