9-(4-Bromobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamide → HCID 22636318, compound

HRID 2415866Notes

Reaction equation

HRID 2415866 reaction equation
[F:1][C:2]([F:26])([F:25])[CH2:3][NH:4][C:5]([C:7]1([CH2:20][CH2:21][CH2:22][CH2:23]Br)[C:19]2[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=2[C:13]2[C:8]1=[CH:9][CH:10]=[CH:11][CH:12]=2)=[O:6].[CH:27]([N:30]1[C:34]2[CH:35]=[CH:36][CH:37]=[CH:38][C:33]=2[N:32]=[C:31]1[N:39]1[CH2:44][CH2:43][NH:42][CH2:41][CH2:40]1)([CH3:29])[CH3:28]>>[F:1][C:2]([F:26])([F:25])[CH2:3][NH:4][C:5]([C:7]1([CH2:20][CH2:21][CH2:22][CH2:23][N:42]2[CH2:43][CH2:44][N:39]([C:31]3[N:30]([CH:27]([CH3:29])[CH3:28])[C:34]4[CH:35]=[CH:36][CH:37]=[CH:38][C:33]=4[N:32]=3)[CH2:40][CH2:41]2)[C:19]2[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=2[C:13]2[C:8]1=[CH:9][CH:10]=[CH:11][CH:12]=2)=[O:6]

Participants

3

Reactant 2

HCID 105264379-(4-Bromobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamideHCID 22636223HCID 22636223, compound

Product 1

HCID 22636318HCID 22636318, compound

Procedure

Prepared analogously to Example 10 from 9-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid-(2,2,2-trifluoro-ethyl)-amide and 1-isopropyl-2-(piperazin-1-yl)-1H-benzimidazole.

Sources & evidence

ORD record
ord-4ca6c4847f344d25866fd2997d38909e
Source dataset
uspto-grants-2004_11
Patent number
US06821967B2

Reaction notes

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