9-(4-Bromobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamide → HCID 22636235, compound

HRID 2415872Notes

Reaction equation

HRID 2415872 reaction equation
[F:1][C:2]([F:26])([F:25])[CH2:3][NH:4][C:5]([C:7]1([CH2:20][CH2:21][CH2:22][CH2:23]Br)[C:19]2[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=2[C:13]2[C:8]1=[CH:9][CH:10]=[CH:11][CH:12]=2)=[O:6].[F:27][C:28]1[CH:29]=[CH:30][C:31]2[N:35]=[C:34]([N:36]3[CH2:41][CH2:40][NH:39][CH2:38][CH2:37]3)[N:33]([CH3:42])[C:32]=2[CH:43]=1>>[F:1][C:2]([F:26])([F:25])[CH2:3][NH:4][C:5]([C:7]1([CH2:20][CH2:21][CH2:22][CH2:23][N:39]2[CH2:40][CH2:41][N:36]([C:34]3[N:33]([CH3:42])[C:32]4[CH:43]=[C:28]([F:27])[CH:29]=[CH:30][C:31]=4[N:35]=3)[CH2:37][CH2:38]2)[C:19]2[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=2[C:13]2[C:8]1=[CH:9][CH:10]=[CH:11][CH:12]=2)=[O:6]

Participants

3

Reactant 2

HCID 105264379-(4-Bromobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamideHCID 22636364HCID 22636364, compound

Product 1

HCID 22636235HCID 22636235, compound

Procedure

Prepared analogously to Example 1e from 9-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid-(2,2,2-trifluoro-ethyl)-amide and 6-fluoro-1-methyl-2-piperazin-1-yl-1H-benzimidazole

Sources & evidence

ORD record
ord-098eed070ce64748b3de1bcecf981eaf
Source dataset
uspto-grants-2004_11
Patent number
US06821967B2

Reaction notes

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