HRID2415873

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：O=C(NCC(F)(F)F)C1(CCCCBr)c2ccccc2-c2ccccc21

HCID10526437

9-(4-Bromobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamide

C20H19BrF3NO

HCID22028248

未命名化合物

PRODUCTS

生成物

结构：Cn1c(N2CCN(CCCCC3(C(=O)NCC(F)(F)F)c4ccccc4-c4ccccc43)CC2)nc2cc(F)ccc21

HCID22636203

未命名化合物

PROCEDURE

实验过程

Prepared analogously to Example 17 from 9-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid-(2,2,2-trifluoro-ethyl)-amide and 5-fluoro-1-methyl-2-piperazin-1-yl-1H-benzimidazole

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-56bed6371f1b4eac8b9e9254f828ee02
来源数据集: uspto-grants-2004_11
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06821967B2
来源说明: uspto-grants-2004_11

反应 SMILES

[F:1][C:2]([F:26])([F:25])[CH2:3][NH:4][C:5]([C:7]1([CH2:20][CH2:21][CH2:22][CH2:23]Br)[C:19]2[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=2[C:13]2[C:8]1=[CH:9][CH:10]=[CH:11][CH:12]=2)=[O:6].[F:27][C:28]1[CH:43]=[CH:42][C:31]2[N:32]([CH3:41])[C:33]([N:35]3[CH2:40][CH2:39][NH:38][CH2:37][CH2:36]3)=[N:34][C:30]=2[CH:29]=1>>[F:1][C:2]([F:26])([F:25])[CH2:3][NH:4][C:5]([C:7]1([CH2:20][CH2:21][CH2:22][CH2:23][N:38]2[CH2:39][CH2:40][N:35]([C:33]3[N:32]([CH3:41])[C:31]4[CH:42]=[CH:43][C:28]([F:27])=[CH:29][C:30]=4[N:34]=3)[CH2:36][CH2:37]2)[C:19]2[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=2[C:13]2[C:8]1=[CH:9][CH:10]=[CH:11][CH:12]=2)=[O:6]