9-(4-Bromobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamide → HCID 22636230, compound

HRID 2415875Notes

Reaction equation

HRID 2415875 reaction equation
[F:1][C:2]([F:26])([F:25])[CH2:3][NH:4][C:5]([C:7]1([CH2:20][CH2:21][CH2:22][CH2:23]Br)[C:19]2[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=2[C:13]2[C:8]1=[CH:9][CH:10]=[CH:11][CH:12]=2)=[O:6].[CH3:27][O:28][C:29]1[C:37]2[N:36]=[C:35]([N:38]3[CH2:43][CH2:42][NH:41][CH2:40][CH2:39]3)[N:34]([CH3:44])[C:33]=2[CH:32]=[CH:31][CH:30]=1>>[F:1][C:2]([F:26])([F:25])[CH2:3][NH:4][C:5]([C:7]1([CH2:20][CH2:21][CH2:22][CH2:23][N:41]2[CH2:42][CH2:43][N:38]([C:35]3[N:34]([CH3:44])[C:33]4[CH:32]=[CH:31][CH:30]=[C:29]([O:28][CH3:27])[C:37]=4[N:36]=3)[CH2:39][CH2:40]2)[C:19]2[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=2[C:13]2[C:8]1=[CH:9][CH:10]=[CH:11][CH:12]=2)=[O:6]

Participants

3

Reactant 2

HCID 105264379-(4-Bromobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamideHCID 22636264HCID 22636264, compound

Product 1

HCID 22636230HCID 22636230, compound

Procedure

Prepared analogously to Example 2b from 9-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid-(2,2,2-trifluoro-ethyl)-amide and 4-methoxy-1-methyl-2-piperazin-1-yl-1H-benzimidazole

Sources & evidence

ORD record
ord-ed7d5cb13f51481281df34ecffdb36ae
Source dataset
uspto-grants-2004_11
Patent number
US06821967B2

Reaction notes

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