2,7-Dichloroquinoline → HCID 22636284, compound

HRID 2415883Notes

Reaction equation

HRID 2415883 reaction equation
[F:1][C:2]([F:31])([F:30])[CH2:3][NH:4][C:5]([C:7]1([CH2:20][CH2:21][CH2:22][CH2:23][N:24]2[CH2:29][CH2:28][NH:27][CH2:26][CH2:25]2)[C:19]2[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=2[C:13]2[C:8]1=[CH:9][CH:10]=[CH:11][CH:12]=2)=[O:6].Cl[C:33]1[CH:42]=[CH:41][C:40]2[C:35](=[CH:36][C:37]([Cl:43])=[CH:38][CH:39]=2)[N:34]=1>>[F:31][C:2]([F:30])([F:1])[CH2:3][NH:4][C:5]([C:7]1([CH2:20][CH2:21][CH2:22][CH2:23][N:24]2[CH2:25][CH2:26][N:27]([C:33]3[CH:42]=[CH:41][C:40]4[C:35](=[CH:36][C:37]([Cl:43])=[CH:38][CH:39]=4)[N:34]=3)[CH2:28][CH2:29]2)[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:13]=2[C:14]2[C:19]1=[CH:18][CH:17]=[CH:16][CH:15]=2)=[O:6]

Participants

3

Reactant 2

HCID 151495062,7-DichloroquinolineHCID 226362859-(4-piperazino-butyl)-9H-fluorene-9-carboxylic acid-(2,2,2-trifluoro-ethyl)-amide

Product 1

HCID 22636284HCID 22636284, compound

Procedure

Prepared analogously to Example 21 from 9-(4-piperazin-1-yl-butyl)-9H-fluorene-9-carboxylic acid-(2,2,2-trifluoro-ethyl)-amide and 2,7-dichloro-quinoline.

Sources & evidence

ORD record
ord-590774dc302b4ade88db6e53474dad1d
Source dataset
uspto-grants-2004_11
Patent number
US06821967B2

Reaction notes

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