HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,5-Dichloroquinoline → 9-{4-[4-(5-chloro-quinolin-2-yl)-piperazin-1-yl]-butyl}-9H-fluorene-9-carboxylic Acid-(2,2,2-trifluoro-ethyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,5-Dichloroquinoline | HCID 676552 | — |
| Reactant | 9-(4-piperazino-butyl)-9H-fluorene-9-carboxylic acid-(2,2,2-trifluoro-ethyl)-amide | HCID 22636285 | — |
| Product | 9-{4-[4-(5-chloro-quinolin-2-yl)-piperazin-1-yl]-butyl}-9H-fluorene-9-carboxylic Acid-(2,2,2-trifluoro-ethyl)-amide | HCID 22636274 | — |
Reaction Steps
Prepared analogously to Example 21 from 9-(4-piperazin-1-yl-butyl)-9H-fluorene-9-carboxylic acid-(2,2,2-trifluoro-ethyl)-amide and 2,5-dichloro-quinoline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06821967B2 |
| Source dataset | uspto-grants-2004_11 |
| ORD ID | ord-f6d7517dcceb4e5abe77573f948b4a9a |
| Source note | uspto-grants-2004_11 |