9-(4-Bromobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamide → HCID 22636332, compound

HRID 2415893Notes

Reaction equation

HRID 2415893 reaction equation
[F:1][C:2]([F:26])([F:25])[CH2:3][NH:4][C:5]([C:7]1([CH2:20][CH2:21][CH2:22][CH2:23]Br)[C:19]2[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=2[C:13]2[C:8]1=[CH:9][CH:10]=[CH:11][CH:12]=2)=[O:6].[Br:27][C:28]1[CH:29]=[CH:30][CH:31]=[C:32]2[C:37]=1[N:36]=[C:35]([N:38]1[CH2:43][CH2:42][NH:41][CH2:40][CH2:39]1)[CH:34]=[CH:33]2>>[F:1][C:2]([F:25])([F:26])[CH2:3][NH:4][C:5]([C:7]1([CH2:20][CH2:21][CH2:22][CH2:23][N:41]2[CH2:42][CH2:43][N:38]([C:35]3[CH:34]=[CH:33][C:32]4[C:37](=[C:28]([Br:27])[CH:29]=[CH:30][CH:31]=4)[N:36]=3)[CH2:39][CH2:40]2)[C:19]2[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=2[C:13]2[C:8]1=[CH:9][CH:10]=[CH:11][CH:12]=2)=[O:6]

Participants

3

Reactant 2

HCID 105264379-(4-Bromobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamideHCID 226362718-Bromo-2-(piperazin-1-yl)quinoline

Product 1

HCID 22636332HCID 22636332, compound

Procedure

Prepared analogously to Example 2 from 9-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid-(2,2,2-trifluoro-ethyl)-amide and 8-bromo-2-piperazin-1-yl-quinoline.

Sources & evidence

ORD record
ord-8e9dffd8331c4d089b84da69b58e0d9d
Source dataset
uspto-grants-2004_11
Patent number
US06821967B2

Reaction notes

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