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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2415920Generated: November 1, 2026

9-(4-Bromobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamide → 9-[4-(4-benzothiazol-2-yl-[1.4]diazepan-1-yl)-butyl]-9H-fluorene-9-carboxylic Acid-(2,2,2-trifluoro-ethyl)-amide

https://huagongshe.com/reaction/2415920

Reaction equation

Participants

RoleNameHCIDCharge
Reactant9-(4-Bromobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamideHCID 10526437—
Reactant2-(1,4-Diazepan-1-yl)benzo[d]thiazoleHCID 16785179—
Product9-[4-(4-benzothiazol-2-yl-[1.4]diazepan-1-yl)-butyl]-9H-fluorene-9-carboxylic Acid-(2,2,2-trifluoro-ethyl)-amideHCID 22636359—

Reaction Steps

Prepared analogously to Example 1 from 9-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid-(2,2,2-trifluoro-ethyl)-amide and 2-[1.4] diazepan-1-yl-benzothiazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06821967B2
Source datasetuspto-grants-2004_11
ORD IDord-a15767d346a54d09b65c4d69efc5e662
Source noteuspto-grants-2004_11