4-Fluorobenzylamine → 9-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid-4-fluoro-benzylamide

HRID 2415921Notes

Reaction equation

HRID 2415921 reaction equation
[F:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6][NH2:7])=[CH:4][CH:3]=1.[Br:10][CH2:11][CH2:12][CH2:13][CH2:14][C:15]1([C:28](Cl)=[O:29])[C:27]2[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=2[C:21]2[C:16]1=[CH:17][CH:18]=[CH:19][CH:20]=2>>[F:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6][NH:7][C:28]([C:15]2([CH2:14][CH2:13][CH2:12][CH2:11][Br:10])[C:27]3[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=3[C:21]3[C:16]2=[CH:17][CH:18]=[CH:19][CH:20]=3)=[O:29])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 673264-FluorobenzylamineHCID 105227589-(4-bromo-butyl)-9H-fluorene-9-carboxylic Acid Chloride

Product 1

HCID 226362389-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid-4-fluoro-benzylamide

Procedure

Prepared analogously to Example 1 from 4-fluoro-benzylamine and 9-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid chloride.

Sources & evidence

ORD record
ord-20e0a5b8a41f49f4ad43f7498ca6e8f9
Source dataset
uspto-grants-2004_11
Patent number
US06821967B2

Reaction notes

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