1H-Benzimidazole, 1-ethyl-2-(1-piperazinyl)- → HCID 22636296, compound

HRID 2415929Notes

Reaction equation

HRID 2415929 reaction equation
[F:1][C:2]1[CH:29]=[CH:28][C:5]([CH2:6][NH:7][C:8]([C:10]2([CH2:23][CH2:24][CH2:25][CH2:26]Br)[C:22]3[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=3[C:16]3[C:11]2=[CH:12][CH:13]=[CH:14][CH:15]=3)=[O:9])=[CH:4][CH:3]=1.[CH2:30]([N:32]1[C:36]2[CH:37]=[CH:38][CH:39]=[CH:40][C:35]=2[N:34]=[C:33]1[N:41]1[CH2:46][CH2:45][NH:44][CH2:43][CH2:42]1)[CH3:31]>>[F:1][C:2]1[CH:29]=[CH:28][C:5]([CH2:6][NH:7][C:8]([C:10]2([CH2:23][CH2:24][CH2:25][CH2:26][N:44]3[CH2:45][CH2:46][N:41]([C:33]4[N:32]([CH2:30][CH3:31])[C:36]5[CH:37]=[CH:38][CH:39]=[CH:40][C:35]=5[N:34]=4)[CH2:42][CH2:43]3)[C:22]3[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=3[C:16]3[C:11]2=[CH:12][CH:13]=[CH:14][CH:15]=3)=[O:9])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 108233681H-Benzimidazole, 1-ethyl-2-(1-piperazinyl)-HCID 226362389-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid-4-fluoro-benzylamide

Product 1

HCID 22636296HCID 22636296, compound

Procedure

Prepared analogously to Example 1 from 9-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid-4-fluoro-benzylamide and 1-ethyl-2-piperazin-1-yl-1H-benzimidazole.

Sources & evidence

ORD record
ord-88566fc9d51c4fbfadeef6d729a41305
Source dataset
uspto-grants-2004_11
Patent number
US06821967B2

Reaction notes

Loading…