5-Chloro-2-piperazin-1-yl-quinoline → HCID 22636295, compound

HRID 2415941Notes

Reaction equation

HRID 2415941 reaction equation
[CH3:1][O:2][C:3]1[CH:30]=[CH:29][C:6]([CH2:7][NH:8][C:9]([C:11]2([CH2:24][CH2:25][CH2:26][CH2:27]Br)[C:23]3[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=3[C:17]3[C:12]2=[CH:13][CH:14]=[CH:15][CH:16]=3)=[O:10])=[CH:5][CH:4]=1.[Cl:31][C:32]1[CH:41]=[CH:40][CH:39]=[C:38]2[C:33]=1[CH:34]=[CH:35][C:36]([N:42]1[CH2:47][CH2:46][NH:45][CH2:44][CH2:43]1)=[N:37]2>>[CH3:1][O:2][C:3]1[CH:30]=[CH:29][C:6]([CH2:7][NH:8][C:9]([C:11]2([CH2:24][CH2:25][CH2:26][CH2:27][N:45]3[CH2:46][CH2:47][N:42]([C:36]4[CH:35]=[CH:34][C:33]5[C:38](=[CH:39][CH:40]=[CH:41][C:32]=5[Cl:31])[N:37]=4)[CH2:43][CH2:44]3)[C:23]3[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=3[C:17]3[C:12]2=[CH:13][CH:14]=[CH:15][CH:16]=3)=[O:10])=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 216804175-Chloro-2-piperazin-1-yl-quinolineHCID 226363179-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid-4-methoxy-benzylamide

Product 1

HCID 22636295HCID 22636295, compound

Procedure

Prepared analogously to Example 2 from 9-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid-4-methoxy-benzylamide and 5-chloro-2-piperazin-1-yl-quinoline.

Sources & evidence

ORD record
ord-c8952c5033654254ac071875b961c4a0
Source dataset
uspto-grants-2004_11
Patent number
US06821967B2

Reaction notes

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