2-Piperazin-1-yl-1,3-benzothiazole → HCID 22636288, compound

HRID 2415944Notes

Reaction equation

HRID 2415944 reaction equation
[CH3:1][O:2][C:3]1[CH:30]=[CH:29][C:6]([CH2:7][NH:8][C:9]([C:11]2([CH2:24][CH2:25][CH2:26][CH2:27]Br)[C:23]3[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=3[C:17]3[C:12]2=[CH:13][CH:14]=[CH:15][CH:16]=3)=[O:10])=[CH:5][CH:4]=1.[N:31]1([C:37]2[S:38][C:39]3[CH:45]=[CH:44][CH:43]=[CH:42][C:40]=3[N:41]=2)[CH2:36][CH2:35][NH:34][CH2:33][CH2:32]1>>[CH3:1][O:2][C:3]1[CH:30]=[CH:29][C:6]([CH2:7][NH:8][C:9]([C:11]2([CH2:24][CH2:25][CH2:26][CH2:27][N:34]3[CH2:35][CH2:36][N:31]([C:37]4[S:38][C:39]5[CH:45]=[CH:44][CH:43]=[CH:42][C:40]=5[N:41]=4)[CH2:32][CH2:33]3)[C:23]3[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=3[C:17]3[C:12]2=[CH:13][CH:14]=[CH:15][CH:16]=3)=[O:10])=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 5921222-Piperazin-1-yl-1,3-benzothiazoleHCID 226363179-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid-4-methoxy-benzylamide

Product 1

HCID 22636288HCID 22636288, compound

Procedure

Prepared analogously to Example 1e from 9-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid-4-methoxy-benzylamide and 2-piperazin-1-yl-benzothiazole.

Sources & evidence

ORD record
ord-67f2c7806d674ebdb14395a1e12da1d4
Source dataset
uspto-grants-2004_11
Patent number
US06821967B2

Reaction notes

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