9-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid-4-methoxy-benzylamide → HCID 23526835, compound

HRID 2415946Notes

Reaction equation

HRID 2415946 reaction equation
[CH3:1][O:2][C:3]1[CH:30]=[CH:29][C:6]([CH2:7][NH:8][C:9]([C:11]2([CH2:24][CH2:25][CH2:26][CH2:27]Br)[C:23]3[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=3[C:17]3[C:12]2=[CH:13][CH:14]=[CH:15][CH:16]=3)=[O:10])=[CH:5][CH:4]=1.[Cl:31][C:32]1[CH:41]=[CH:40][CH:39]=[C:38]2[C:33]=1[CH:34]=[CH:35][C:36]([N:42]1[CH2:47][C@H:46]([CH3:48])[NH:45][C@H:44]([CH3:49])[CH2:43]1)=[N:37]2>>[CH3:1][O:2][C:3]1[CH:30]=[CH:29][C:6]([CH2:7][NH:8][C:9]([C:11]2([CH2:24][CH2:25][CH2:26][CH2:27][N:45]3[C@H:46]([CH3:48])[CH2:47][N:42]([C:36]4[CH:35]=[CH:34][C:33]5[C:38](=[CH:39][CH:40]=[CH:41][C:32]=5[Cl:31])[N:37]=4)[CH2:43][C@@H:44]3[CH3:49])[C:23]3[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=3[C:17]3[C:12]2=[CH:13][CH:14]=[CH:15][CH:16]=3)=[O:10])=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 226363179-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid-4-methoxy-benzylamideHCID 69891318HCID 69891318, compound

Product 1

HCID 23526835HCID 23526835, compound

Procedure

Prepared analogously to Example 2 from 9-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid-4-methoxy-benzylamide and 5-chloro-2-(cis-3,5-dimethyl-piperazin-1-yl)-quinoline.

Sources & evidence

ORD record
ord-23a0ac03671247269bc6e04d92dd7500
Source dataset
uspto-grants-2004_11
Patent number
US06821967B2

Reaction notes

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