2,4-Difluorobenzylamine → HCID 22636315, compound
Reaction equation
[F:1][C:2]1[CH:9]=[C:8]([F:10])[CH:7]=[CH:6][C:3]=1[CH2:4][NH2:5].[Br:11][CH2:12][CH2:13][CH2:14][CH2:15][C:16]1([C:29](Cl)=[O:30])[C:28]2[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=2[C:22]2[C:17]1=[CH:18][CH:19]=[CH:20][CH:21]=2>>[F:1][C:2]1[CH:9]=[C:8]([F:10])[CH:7]=[CH:6][C:3]=1[CH2:4][NH:5][C:29]([C:16]1([CH2:15][CH2:14][CH2:13][CH2:12][Br:11])[C:28]2[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=2[C:22]2[C:17]1=[CH:18][CH:19]=[CH:20][CH:21]=2)=[O:30]Participants
3
Procedure
Prepared analogously to Example 1 from 2,4-difluorbenzylamine and 9-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid chloride.
Sources & evidence
- ORD record
- ord-64021a32d60943efa73a9394eefbfce8
- Source dataset
- uspto-grants-2004_11
- Patent number
- US06821967B2
Reaction notes
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