4-Pyridinemethanamine → 9-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid-(pyridin-4-ylmethyl)-amide

HRID 2415962Notes

Reaction equation

HRID 2415962 reaction equation
[NH2:1][CH2:2][C:3]1[CH:8]=[CH:7][N:6]=[CH:5][CH:4]=1.[Br:9][CH2:10][CH2:11][CH2:12][CH2:13][C:14]1([C:27](Cl)=[O:28])[C:26]2[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=2[C:20]2[C:15]1=[CH:16][CH:17]=[CH:18][CH:19]=2>>[N:6]1[CH:7]=[CH:8][C:3]([CH2:2][NH:1][C:27]([C:14]2([CH2:13][CH2:12][CH2:11][CH2:10][Br:9])[C:26]3[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=3[C:20]3[C:15]2=[CH:16][CH:17]=[CH:18][CH:19]=3)=[O:28])=[CH:4][CH:5]=1

Participants

3

Reactant 2

HCID 773174-PyridinemethanamineHCID 105227589-(4-bromo-butyl)-9H-fluorene-9-carboxylic Acid Chloride

Product 1

HCID 226361749-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid-(pyridin-4-ylmethyl)-amide

Procedure

Prepared analogously to Example 1 from 4-(aminomethyl)-pyridine and 9-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid chloride.

Sources & evidence

ORD record
ord-ab9740bd22df47879e36073140b83527
Source dataset
uspto-grants-2004_11
Patent number
US06821967B2

Reaction notes

Loading…