2-Pyridinemethanamine → 9-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid-(pyridin-2-ylmethyl)-amide

HRID 2415964Notes

Reaction equation

HRID 2415964 reaction equation
[NH2:1][CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][N:4]=1.[Br:9][CH2:10][CH2:11][CH2:12][CH2:13][C:14]1([C:27](Cl)=[O:28])[C:26]2[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=2[C:20]2[C:15]1=[CH:16][CH:17]=[CH:18][CH:19]=2>>[N:4]1[CH:5]=[CH:6][CH:7]=[CH:8][C:3]=1[CH2:2][NH:1][C:27]([C:14]1([CH2:13][CH2:12][CH2:11][CH2:10][Br:9])[C:26]2[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=2[C:20]2[C:15]1=[CH:16][CH:17]=[CH:18][CH:19]=2)=[O:28]

Participants

3

Reactant 2

HCID 195092-PyridinemethanamineHCID 105227589-(4-bromo-butyl)-9H-fluorene-9-carboxylic Acid Chloride

Product 1

HCID 226362709-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid-(pyridin-2-ylmethyl)-amide

Procedure

Prepared analogously to Example 1 from 2-(aminomethyl)-pyridine and 9-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid chloride.

Sources & evidence

ORD record
ord-8efd5291905c4d53bf1843905bd5a4a9
Source dataset
uspto-grants-2004_11
Patent number
US06821967B2

Reaction notes

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