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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2415980Generated: October 26, 2026

2-Piperazin-1-yl-1,3-benzothiazole → 9-[4-(4-benzothiazol-2-yl-piperazin-1-yl)-butyl]-9H-xanthene-9-carboxylic acid-(2,2,2-trifluoro-ethyl)-amide

https://huagongshe.com/reaction/2415980

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Piperazin-1-yl-1,3-benzothiazoleHCID 592122—
Reactant4-[9-(2,2,2-Trifluoroethylcarbamoyl)-9H-xanthen-9-yl]butyl bromideHCID 22180203—
Product9-[4-(4-benzothiazol-2-yl-piperazin-1-yl)-butyl]-9H-xanthene-9-carboxylic acid-(2,2,2-trifluoro-ethyl)-amideHCID 22636211—

Reaction Steps

Prepared analogously to Example 1f from 9-(4-bromo-butyl)-9H-xanthene-9-carboxylic acid-(2,2,2-trifluoro-ethyl)-amide and 2-(piperazin-1-yl)-benzothiazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06821967B2
Source datasetuspto-grants-2004_11
ORD IDord-ba1728338770415b9fcc6d48c6316094
Source noteuspto-grants-2004_11