HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Chloro-2-piperazin-1-yl-quinoline → 9-{4-[4-(5-chloro-quinolin-2-yl)-piperazin-1-yl]-butyl}-9H-xanthene-9-carboxylic Acid-(2,2,2-trifluoro-ethyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Chloro-2-piperazin-1-yl-quinoline | HCID 21680417 | — |
| Reactant | 4-[9-(2,2,2-Trifluoroethylcarbamoyl)-9H-xanthen-9-yl]butyl bromide | HCID 22180203 | — |
| Product | 9-{4-[4-(5-chloro-quinolin-2-yl)-piperazin-1-yl]-butyl}-9H-xanthene-9-carboxylic Acid-(2,2,2-trifluoro-ethyl)-amide | HCID 22636325 | — |
Reaction Steps
Prepared analogously to Example 2 from 9-(4-bromo-butyl)-9H-xanthene-9-carboxylic acid-(2,2,2-trifluoro-ethyl)-amide and 5-chloro-2-piperazin-1-yl-quinoline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06821967B2 |
| Source dataset | uspto-grants-2004_11 |
| ORD ID | ord-9d64d47d5b2742c09b2bf78f2e01befa |
| Source note | uspto-grants-2004_11 |