4-[9-(2,2,2-Trifluoroethylcarbamoyl)-9H-xanthen-9-yl]butyl bromide → HCID 23526836, compound

HRID 2415992Notes

Reaction equation

HRID 2415992 reaction equation
[F:1][C:2]([F:27])([F:26])[CH2:3][NH:4][C:5]([C:7]1([CH2:21][CH2:22][CH2:23][CH2:24]Br)[C:20]2[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=2[O:14][C:13]2[C:8]1=[CH:9][CH:10]=[CH:11][CH:12]=2)=[O:6].[Cl:28][C:29]1[CH:38]=[CH:37][CH:36]=[C:35]2[C:30]=1[CH:31]=[CH:32][C:33]([N:39]1[CH2:44][C@H:43]([CH3:45])[NH:42][C@H:41]([CH3:46])[CH2:40]1)=[N:34]2>>[F:1][C:2]([F:27])([F:26])[CH2:3][NH:4][C:5]([C:7]1([CH2:21][CH2:22][CH2:23][CH2:24][N:42]2[C@H:43]([CH3:45])[CH2:44][N:39]([C:33]3[CH:32]=[CH:31][C:30]4[C:35](=[CH:36][CH:37]=[CH:38][C:29]=4[Cl:28])[N:34]=3)[CH2:40][C@@H:41]2[CH3:46])[C:20]2[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=2[O:14][C:13]2[C:8]1=[CH:9][CH:10]=[CH:11][CH:12]=2)=[O:6]

Participants

3

Reactant 2

HCID 221802034-[9-(2,2,2-Trifluoroethylcarbamoyl)-9H-xanthen-9-yl]butyl bromideHCID 69891318HCID 69891318, compound

Product 1

HCID 23526836HCID 23526836, compound

Procedure

Prepared analogously to Example 1 from 9-(4-bromo-butyl)-9H-xanthene-9-carboxylic acid-(2,2,2-trifluoro-ethyl)-amide and 5-chloro-2-(cis-3,5-dimethyl-piperazin-1-yl)-quinoline.

Sources & evidence

ORD record
ord-7a9f6a624ada4f95a811401e4550d27c
Source dataset
uspto-grants-2004_11
Patent number
US06821967B2

Reaction notes

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