Quipazine → 9-[4-(4-quinolin-2-yl-piperazin-1-yl)-butyl]-9H-xanthene-9-carboxylic Acid-Butylamide

HRID 2415999Notes

Reaction equation

HRID 2415999 reaction equation
[CH2:1]([NH:5][C:6]([C:8]1([CH2:22][CH2:23][CH2:24][CH2:25]Br)[C:21]2[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=2[O:15][C:14]2[C:9]1=[CH:10][CH:11]=[CH:12][CH:13]=2)=[O:7])[CH2:2][CH2:3][CH3:4].[N:27]1([C:33]2[CH:42]=[CH:41][C:40]3[C:35](=[CH:36][CH:37]=[CH:38][CH:39]=3)[N:34]=2)[CH2:32][CH2:31][NH:30][CH2:29][CH2:28]1>>[CH2:1]([NH:5][C:6]([C:8]1([CH2:22][CH2:23][CH2:24][CH2:25][N:30]2[CH2:31][CH2:32][N:27]([C:33]3[CH:42]=[CH:41][C:40]4[C:35](=[CH:36][CH:37]=[CH:38][CH:39]=4)[N:34]=3)[CH2:28][CH2:29]2)[C:21]2[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=2[O:15][C:14]2[C:9]1=[CH:10][CH:11]=[CH:12][CH:13]=2)=[O:7])[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 5011QuipazineHCID 226361829-(4-bromo-butyl)-9H-xanthene-9-carboxylic acid-butylamide

Product 1

HCID 226362829-[4-(4-quinolin-2-yl-piperazin-1-yl)-butyl]-9H-xanthene-9-carboxylic Acid-Butylamide

Procedure

Prepared analogously to Example 1 from 9-(4-bromo-butyl)-9H-xanthene-9-carboxylic acid-butylamide and 2-piperazin-1-yl-quinoline.

Sources & evidence

ORD record
ord-be4d6055b2ec48f897ef19be88a49ebb
Source dataset
uspto-grants-2004_11
Patent number
US06821967B2

Reaction notes

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